Cryonics Revival Scenarios & Potential Roadmaps & Hypotheses

Revolutionary treatment could stop and reverse early-stage Alzheimer’s These findings suggest that the neuronal dysfunctions caused by Alzheimer’s could potentially be reversed by novel protein drug. In the battle against Alzheimer’s disease, a team of researchers at the Technical University of Munich (TUM) has made significant strides with a promising new therapeutic approach. They have […]

Scientists have identified a unique form of cell messaging occurring in the human brain, revealing just how much we still have to learn about its mysterious inner workings. Excitingly, the discovery hints that our brains might be even more powerful units of computation than we realized. Back in 2020, researchers from institutes in Germany and […]

For decades, researchers have debated whether brain cells called astrocytes can signal like neurons. Researchers recently published the best evidence yet that some astrocytes are part of the electrical conversation. A brain is nothing if not communicative. Neurons are the chatterboxes of this conversational organ, and they speak with one another by exchanging pulses of […]

The realm of neuroscience is constantly evolving, bringing to light new discoveries that change our understanding of the human brain, behavior, and cognition. From the intricate dance between gut health and mental well-being to the unexpected roles of overlooked brain regions and the neural underpinnings of our moral judgments, recent studies have provided fascinating insights. […]

Summary: Researchers have identified five biological variants of Alzheimer’s disease through cerebrospinal fluid analysis, shedding new light on the complexity of the condition. These variants differ in amyloid production, blood-brain barrier integrity, nerve cell growth, protein synthesis, and immune system functioning. This breakthrough highlights the importance of personalized medicine in Alzheimer’s treatment, as a drug […]

Researchers taking part in the Human Brain Project have identified a mathematical rule that governs the distribution of neurons in our brains. The rule predicts how neurons are distributed in different parts of the brain, and could help scientists create precise models to understand how the brain works and develop new treatments for neurological diseases. […]

A groundbreaking AI method may accelerate cognitive neuroscience research. Scientific research in complex fields such as neuroscience is getting a boost from artificial intelligence (AI) machine learning. A new study by researchers at Ecole Polytechnique Fédérale de Lausanne (EPFL) in Lausanne, Switzerland, and Harvard University in Cambridge, Massachusetts, U.S., shows how AI has the potential […]

The “circuit” metaphor of the brain is as indisputable as it is familiar: Neurons forge direct physical connections to create functional networks, for instance to store memories or produce thoughts. But the metaphor is also incomplete. What drives these circuits and networks to come together? New evidence suggests that at least some of this coordination […]

Multiple interacting spirals organize brain activity flow. Credit: Gong et al. University of Sydney and Fudan University scientists have discovered human brain signals traveling across the outer layer of neural tissue that naturally arrange themselves to resemble swirling spirals. The research, published today in Nature Human Behaviour, indicates these ubiquitous spirals, which are brain signals […]

Three new books lay bare the weirdness of how our brains process the world around us. By Matthew Hutson August 25, 2021 https://www-technologyreview-com.cdn.ampproject.org/c/s/www.technologyreview.com/2021/08/25/1032121/brains-controlled-hallucination/amp/

To perform various maintenance and protective tasks, the brain contains a large population of microglia alongside its neurons. These glia include astrocytes, which, among their many other tasks, are responsible for aiding neurons with metabolism. For example, after a neuron fires, the glutamate used in that firing is taken up by an astrocyte, processed into […]

From probing neurons to grabbing microscope slides, cutting-edge equipment is helping neuroscientists advance research faster Cliff Slaughterbeck, Ph.D., is showing off some of his babies. “Nobody sells this whole thing off the shelf,” he said, gesturing at a microscope housed in a large black box, one of eight identical rigs set up in the Allen […]

Scientists have recently identified a unique form of cell messaging occurring in the human brain that’s not been seen before. Excitingly, the discovery hints that our brains might be even more powerful units of computation than we realized. Back in 2020, researchers from institutes in Germany and Greece reported a mechanism in the brain’s outer […]

A new study reveals that the brain can switch between slow and fast integration of information, allowing it to modulate the timescales on which it operates. The study also provides insight into how the structure of neural networks determines the speed at which information is integrated, which may have implications for future research on brain […]

The word “brainwashing” usually triggers negative associations. But our brain health for sure depends on it. Scientists at the University of Oslo have recently made new and important discoveries about how and why this happens when we are sleeping. The blood vessels in the brain constrict and dilate in certain patterns while we sleep and […]

Machine-learning models like the one that powers ChatGPT are generating essays, short stories, and entire podcasts. But scientists are looking into another way of computing that could be just as efficient and powerful, and it’s in our brains. In a new article published on Tuesday in Frontiers, a large international collaboration led by researchers at […]

The phenomenon of criticality can explain the sudden emergence of new properties in a wide range of complex systems, from avalanches to flocks of birds to stock market crashes. Neuroscientists are now seeking evidence that criticality is at work in the brain’s networks of neurons. https://www.quantamagazine.org/videos/could-one-physics-theory-unlock-the-mysteries-of-the-brain/

A controversial theory suggests that perception, motor control, memory and other brain functions all depend on comparisons between ongoing actual experiences and the brain’s modeled expectations. Some neuroscientists favor a predictive coding explanation for how the brain works, in which perception may be thought of as a “controlled hallucination.” This theory emphasizes the brain’s expectations […]

The study shows that our brains exist between chaos and stability—a finding that could be used to help tweak them either way. By Jessica Hamzelou February 7, 2023 Our brains exist in a state somewhere between stability and chaos as they help us make sense of the world, according to recordings of brain activity taken […]

Summary: Study reveals a signaling pathway that controls the formation of synapses between pyramidal neurons and inhibitory neurons expressing the parvalbumin protein. Source: King’s College London New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has demonstrated that brain wiring requires the control of local protein synthesis at the […]

Summary: Whole brain functional connectivity patterns successfully classified six basic emotions from neutral expressions. Source: Science China Press Emotions are an important part of human intelligence. Identifying specific emotional categories from complex neural patterns (i.e., the neural decoding of emotional information) is a key issue in current emotion research. The categorial emotion models have suggested […]

It’s a good site to check: https://www.cell.com/trends/neurosciences/home

No matter how hard they try, brain scientists and cognitive psychologists will never find a copy of Beethoven’s 5th Symphony in the brain – or copies of words, pictures, grammatical rules or any other kinds of environmental stimuli. The human brain isn’t really empty, of course. But it does not contain most of the things […]

Summary: Study identifies brain areas where the meaning of words is retrieved from memory and processed during language comprehension. Source: Medical College of Wisconsin A new study by researchers at the Medical College of Wisconsin (MCW) reveals the areas of the brain where the meanings of words are retrieved from memory and processed during language […]

Summary: Researchers have mapped four new areas of the human anterior prefrontal cortex that play critical roles in cognitive processing. Two of these newly mapped areas are larger in females than in males. Source: Human Brain Project Researchers of the Human Brain Project (HBP) have mapped four new areas of the human anterior prefrontal cortex […]

Researchers at the University of Utah (U of U) Health report that a fungus that is a common cause of fungal meningitis undergoes a transformation once it enters the body, allowing it to infect the brain. Studies in mice showed that as the fungal intruder travels through the body, it shrinks and acquires characteristics that […]

You may think that a good night’s sleep should be uninterrupted. But in fact, the neurotransmitter noradrenaline causes you to wake up more than 100 times a night, new research from the University of Copenhagen concludes. It is perfectly normal and may even indicate that you have slept well. You wake up. The alarm clock […]

Another place to find new ideas: https://www.sciencedaily.com/news/mind_brain/neuroscience/ to discover and become more knowledgeable about our future.

The Johns Hopkins Medicine Brain Science Institute’s mission is to solve fundamental questions about brain development, function and disease and to translate this knowledge into effective therapies to support brain health and healing. Launched in 2007, the Brain Science Institute unified the tremendous thought leadership across the Johns Hopkins community in the brain sciences and […]

This network had mostly been studied in English speakers. The brain’s language processing network is mostly located in the left hemisphere. (Image credit: Christine Daniloff, MIT; iStock image) Japanese, Italian, Ukrainian, Swahili, Tagalog and dozens of other spoken languages cause the same “universal language network” to light up in the brains of native speakers. This […]

APPLY NOW FOR THE OPENSCOPE PROGRAM OpenScope opens the Allen Brain Observatory pipeline to the community, enabling theoretical, computational, and experimental scientists to test sophisticated hypotheses on brain function in a process analogous to astronomical observatories that survey the night sky. OpenScope is accepting experimental proposals from scientists outside the Allen Institute, which will be […]

Dear Colleague, This is our final call for applications for the 2022 Next Generation Leaders Council. The application deadline has been extended to August 1, 2022. This council is affiliated with the Allen Institute for Brain Science, the Allen Institute for Neural Dynamics, and the MindScope Program, the three neuroscience divisions within the Allen Institute. […]

Experiencing a frightening event is likely something you’ll never forget. But why does it stay with you when other kinds of occurrences become increasingly difficult to recall with the passage of time? A team of neuroscientists from the Tulane University School of Science and Engineering and Tufts University School of Medicine have been studying the […]

Summary: Researchers report they have identified the first natural light-gated potassium channel-rhodopsins. Source: Baylor College of Medicine A key approach to understanding the brain is to observe the behavioral effects of turning on specific populations of neurons. One of the most popular approaches to controlling neuronal activity in model systems is called optogenetics and depends […]

When food has been in short supply for a long time and body weight falls below a critical threshold, the brain reduces its energy consumption by changing how it processes information. When our phones and computers run out of power, their glowing screens go dark and they die a sort of digital death. But switch […]

Is your brain like a computer? An old-timey telephone switchboard? A dense urban landscape? These are all common analogies for the brain, but most who use them know they are wholly imperfect comparisons. We humans thrive on metaphor and succinct stories, but our brains themselves can’t be summed up so easily. Many fields of science […]

Dear Colleague, We are writing to remind you that applications for our 2022 Next Generation Leaders Council cohort are now open. This council is affiliated with the Allen Institute for Brain Science, the Allen Institute for Neural Dynamics, and the MindScope Program, the three neuroscience divisions within the Allen Institute. Comprised of early career investigators […]

Scientists have known for centuries that the brain is the seat of human thought, but we’re still in the dark about how it works. For Brain Awareness Week 2022, Lab Notes asked four neuroscientists to get into the weeds with us about why the brain is so complicated and hard to understand. Do we have […]

Source: Using an advanced microscopy technique, researchers discovered the role adhesion molecules play in guiding neurons into their correct location. Source: Yale In a new study, Yale researchers used an advanced microscopy technique that allowed them to follow a single neuron in the embryo of a worm as it found its neurological home. The research […]

Summary: Neuroimaging reveals surprisingly few links between white matter structure and reading ability in children. Source: MIT When we read, information zips between language processing centers in different parts of the brain, traveling along neural highways in the white matter. This coordinated activity allows us to decipher words and comprehend their meaning. Many neuroscientists suspect […]

The MindScope program at the Allen Institute seeks to understand the transformations, sometimes called computations, in coding and decoding that lead from photons to behavior and conscious experience by observing, perturbing and modeling the physical transformations of signals in the cortical-thalamic visual system within a few perception-action cycles. We generate data and discoveries through the […]

Some neurons in the brain become active specifically in addition tasks, others in subtraction. Credit: Christian Burkert/Volkswagen-Stiftung/University of Bonn The brain has neurons that fire specifically during certain mathematical operations. This is shown by a recent study conducted by the Universities of Tübingen and Bonn. The findings indicate that some of the neurons detected are […]

For neuroscientists who study our own brains, the quest to understand the human brain contains many paradoxes. We still don’t understand the features that give human brains their unique cognitive abilities. The human brain is larger compared to our body size than that of many other animals, but it’s nowhere near the largest brain out […]

https://portal.brain-map.org/

Like you may noticed, we are very far from knowing every functions from the brain(s). Our knowledge in neurology is far from being complete.

Summary: A new system within the brain uses for information processing and memory storage has been discovered. The findings provide novel insight into how the brain functions. Source: NYU A team of scientists has uncovered a system in the brain used in the processing of information and in the storing of memories—akin to how railroad […]

A new experiment probed how the human brain encodes and processes the flow of time. When we recall past events in our lives, we can often mentally replay an experience in the exact sequential order that it happened. Revisiting these episodic memories may feel like a seamless and ordinary activity, but the ability for our […]

A commonly held view is that when brain cells die, it is an irreversible, final state. Within less than 40 seconds of oxygen deprivation, the human brain’s interneuronal activity ceases and becomes electrically inactive. The brain’s ion gradients begin to degrade within minutes, as depolarization proliferates as a surge of electrochemical energy is released as […]

The more we will attract neurologists/cryonicists in Cryonics, the best we will be. Neurologists that believe in Cryonics.

The Brain Modeling Toolkit is a Python-based open software package for building, simulating, and analyzing large-scale neural network models. It supports the building and simulation of models at various scales. The Brain Modeling Toolkit is linked to SONATA, a standardized data format for storing networks and simulations. These software tools together support the development and […]

The human gut harbors a dynamic and complex microbial ecosystem, consisting of approximately 1 kg of bacteria in the average adult, approximately the weight of the human brain. The evolutionary formation of a complex gut microbiota in mammals has played an important role in enabling brain development and perhaps sophisticated social interaction. Genes within the […]

Summary: Study reports a pervasive neuromodulation system strongly influences sound processing in a key auditory region of the brain. Findings suggest acetylcholine may assist in the brain’s ability to distinguish speech from other noise. Source: Lehigh University For the first time, researchers have provided physiological evidence that a pervasive neuromodulation system – a group of […]

October 21, 2020 Cognitive neuroscientists have long debated about whether people have visual-like “pictures in the brain” that we activate when we think of them, or whether representations are more semantically organized in sets of features. So, for example, if asked to think of a blond person, will someone conjure in their “mind’s eye,” a […]

Through the NIH-funded 4D Nucleome program, new efforts are underway to model the nucleus in human stem cells and capture 3D genome organization in mouse and human brain cells New research is underway to better understand the nucleus, the control center of our cells. Teams from two divisions of the Allen Institute, the Allen Institute […]

Using a technique that simultaneously captures different kinds of features from each cell, researchers lay groundwork for a “family tree” of the brain. A technique that captures information about a neuron’s 3D shape, electrical properties, and its genes is giving scientists a new way to look at cell types in the mouse brain and the […]

Human brain maps are a dime a dozen these days. Maps that detail neurons in a certain region. Maps that draw out functional connections between those cells. Maps that dive deeper into gene expression. Or even meta-maps that combine all of the above. But have you ever wondered: how well do those maps represent my […]