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{"id":2006,"date":"2025-06-22T00:56:54","date_gmt":"2025-06-22T00:56:54","guid":{"rendered":"https:\/\/jonathandespres.com\/cryonicsrevival\/?p=2006"},"modified":"2025-06-22T00:56:54","modified_gmt":"2025-06-22T00:56:54","slug":"from-alcor","status":"publish","type":"post","link":"https:\/\/jonathandespres.com\/cryonicsrevival\/2025\/06\/22\/from-alcor\/","title":{"rendered":"From Alcor"},"content":{"rendered":"<div>\n<div>\n<div class=\"m_-4066407715716347716responsive-container\">\n<div>\n<div>\n<div>\n<table role=\"presentation\" width=\"100%\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td>\n<table role=\"presentation\" width=\"100%\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td>\n<div>\n<div>\n<div>\n<p><img class=\"an1\" draggable=\"false\" src=\"https:\/\/fonts.gstatic.com\/s\/e\/notoemoji\/16.0\/1f52c\/32.png\" alt=\"\ud83d\udd2c\" data-emoji=\"\ud83d\udd2c\" aria-label=\"\ud83d\udd2c\" \/><b>\u00a0Why Organ Preservation Matters<\/b><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table role=\"presentation\" border=\"0\" width=\"100%\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td>\n<table role=\"presentation\" border=\"0\" width=\"100%\" cellspacing=\"0\" cellpadding=\"0\" align=\"center\">\n<tbody>\n<tr>\n<td>\n<div>\n<div role=\"figure\" aria-label=\"\"><a href=\"http:\/\/go.pardot.com\/e\/986231\/2025-06-13\/h3jnf\/1607203614\/h\/4zL-zuuGx3ESDDN3ibBQh4abhwLPoWol6FoImFg_UIU\" target=\"_blank\" rel=\"noopener\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=http:\/\/go.pardot.com\/e\/986231\/2025-06-13\/h3jnf\/1607203614\/h\/4zL-zuuGx3ESDDN3ibBQh4abhwLPoWol6FoImFg_UIU&amp;source=gmail&amp;ust=1750639894240000&amp;usg=AOvVaw1H2inuLscii9A1atGPWPK5\"><img class=\"CToWUd\" src=\"https:\/\/ci3.googleusercontent.com\/meips\/ADKq_NbPsfstHNPSO5TL1Hui9AkFsXhSBq3Iz2gsdPne51Ly95nfwt4irnmr9K8fL2GpZwP8jaJ_3Dc6Hj5VoAMtyktQQZnE2qGa3EHcxcO6qIpvtBiLrH93VoMH4AWEEu2z_pXXuNYe9e5ii0Ztc7aK1I1KW_pTlnNfHMA8xLmk7BStmrnj7NfPPpxgOz7J1lRiteCWXTE3D7TCaP1Yo0lzU5m89HWFoww94g8D=s0-d-e1-ft#https:\/\/alcorfoundation.cdn.salesforce-experience.com\/cms\/delivery\/media\/MCGVSLULY5TNCHNDURMJILFYP6TU?channelId=0apRm00000007kf&amp;oid=00D1I0000000aXy\" alt=\"\" width=\"564\" data-bit=\"iit\" \/><\/a><\/div>\n<\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<div>\n<div class=\"m_-4066407715716347716responsive-container\">\n<div>\n<div>\n<div>\n<table role=\"presentation\" width=\"100%\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td>\n<table role=\"presentation\" width=\"100%\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td>\n<div>\n<div>\n<p><b>The Kidney Connection<\/b><\/p>\n<p>If you&#8217;ve been following our content, you&#8217;ve probably noticed we mention kidney experiments quite a bit. I&#8217;ve gotten multiple members asking me the same question: why are we focusing on kidneys when what cryonicists really care about is the brain? Fair question \u2013 here&#8217;s why this type of research is crucial for our goals.<\/p>\n<p><b>It&#8217;s About Validation:<\/b>\u00a0One of the best test of any preservation protocol is whether the organ actually works after cryopreservation and thawing. With kidneys, we can do transplants to prove functionality. You can&#8217;t transplant a brain (yet), so kidneys give us the gold standard for testing our methods.<\/p>\n<p><b>Perfect Starting Point:<\/b>\u00a0Kidneys have remarkably simple vascular architecture \u2013 one artery going in, one vein coming out. Compared to organs with multiple arteries, it&#8217;s a much simpler system to perfuse and cryoprotect. They also have challenging internal regions that are harder to preserve, making them an excellent testing ground for our techniques.<\/p>\n<p><b>Size Matters:<\/b>\u00a0Other research groups work with mouse, rat, and rabbit kidneys, which are tiny. We&#8217;re using pig kidneys, which are human-sized. No one has ever successfully cryopreserved, thawed, and transplanted a human-sized organ. If we crack that, it&#8217;s a massive step for both cryonics and medicine in general \u2013 imagine being able to bank organs for transplant instead of the current system where kidneys must be transplanted within 24-36 hours or they&#8217;re lost forever.<\/p>\n<p><b>The Logic:<\/b>\u00a0If you can&#8217;t successfully restore a preserved kidney, you can&#8217;t preserve a whole organism. Every organ presents different challenges, but we&#8217;re starting with the most straightforward one and working our way up to more complex organs like liver, lungs, heart, and yes, brain.<\/p>\n<p><b>We&#8217;re Not Ignoring Brains:<\/b>\u00a0The research team is actually working on brain tissue experiments in parallel. But the kidney work gives us publishable, credible results that provide both experience and legitimacy to\u00a0<span class=\"il\">Alcor<\/span>\u00a0while we develop protocols that apply across organ systems.<\/p>\n<p><b>The bottom line:<\/b>\u00a0Better organ preservation research leads to better member outcomes. If you&#8217;d like to accelerate this work, please consider a\u00a0<a href=\"http:\/\/go.pardot.com\/e\/986231\/ct-donate-module-partial-page-\/h3jnx\/1607203614\/h\/4zL-zuuGx3ESDDN3ibBQh4abhwLPoWol6FoImFg_UIU\" target=\"_blank\" rel=\"noopener\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=http:\/\/go.pardot.com\/e\/986231\/ct-donate-module-partial-page-\/h3jnx\/1607203614\/h\/4zL-zuuGx3ESDDN3ibBQh4abhwLPoWol6FoImFg_UIU&amp;source=gmail&amp;ust=1750639894240000&amp;usg=AOvVaw12I-yi06-YPmgogIBcVBia\">donation<\/a>\u00a0to support our science. We&#8217;re working on multiple fronts simultaneously \u2013 kidney research that advances the field while building toward our aspirational goals.<\/p>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0Why Organ Preservation Matters The Kidney Connection If you&#8217;ve been following our content, you&#8217;ve probably noticed we mention kidney experiments quite a bit. I&#8217;ve gotten multiple members asking me the same question: why are we focusing on kidneys when what cryonicists really care about is the brain? Fair question \u2013 here&#8217;s why this type of [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[35],"tags":[],"_links":{"self":[{"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/posts\/2006"}],"collection":[{"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/comments?post=2006"}],"version-history":[{"count":1,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/posts\/2006\/revisions"}],"predecessor-version":[{"id":2007,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/posts\/2006\/revisions\/2007"}],"wp:attachment":[{"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/media?parent=2006"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/categories?post=2006"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/tags?post=2006"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}