Whole-Brain Imaging of Neuronal Activity in Zebrafish
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\nScientists at the Howard Hughes Medical Institute studied live zebrafish larvae using a novel approach that combined genetics, calcium imaging, and light-sheet microscopy to observe whole brain activity.<\/p>\n

This method allowed scientists to record the activity of more than 80% of the 100,000 neurons in the zebrafish brain at single-cell resolution.<\/p>\n

Here is how it works (from journal Nature):<\/p>\n

The imaging system involves using genetically engineered zebrafish.<\/p>\n

The fish’s neurons make a protein that fluoresces in response to fluctuations in the concentration of calcium ions, which occur when nerve cells fire.<\/p>\n

A microscope sends sheets of light rather than a conventional beam through the fish’s brain, and a detector captures the signals like a viewer watching a cinema screen. <\/p>\n

(Video Credit: Misha Ahrens & Philipp Keller, Howard Hughes Medical Institute)<\/p>\n

\ud83d\udccdLinks to References \/ More Info in Comments<\/p>\n

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\n\u2b50\ufe0f\u27a1\ufe0f FOLLOW for Neuroscience & Digital Health<\/p>\n

hashtag#neuroscience hashtag#health hashtag#mentalhealth
\nhashtag#biotechnology hashtag#psychology hashtag#digitalhealth<\/p>\n","protected":false},"excerpt":{"rendered":"

Whole-Brain Imaging of Neuronal Activity in Zebrafish \u2026 Scientists at the Howard Hughes Medical Institute studied live zebrafish larvae using a novel approach that combined genetics, calcium imaging, and light-sheet microscopy to observe whole brain activity. This method allowed scientists to record the activity of more than 80% of the 100,000 neurons in the zebrafish […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[13],"tags":[],"_links":{"self":[{"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/posts\/1972"}],"collection":[{"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/comments?post=1972"}],"version-history":[{"count":1,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/posts\/1972\/revisions"}],"predecessor-version":[{"id":1973,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/posts\/1972\/revisions\/1973"}],"wp:attachment":[{"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/media?parent=1972"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/categories?post=1972"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/tags?post=1972"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}