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{"id":1824,"date":"2024-05-07T23:08:42","date_gmt":"2024-05-07T23:08:42","guid":{"rendered":"https:\/\/jonathandespres.com\/cryonicsrevival\/?p=1824"},"modified":"2024-05-07T23:08:42","modified_gmt":"2024-05-07T23:08:42","slug":"this-ai-just-designed-a-more-precise-crispr-gene-editor-for-human-cells-from-scratch","status":"publish","type":"post","link":"https:\/\/jonathandespres.com\/cryonicsrevival\/2024\/05\/07\/this-ai-just-designed-a-more-precise-crispr-gene-editor-for-human-cells-from-scratch\/","title":{"rendered":"This AI Just Designed a More Precise CRISPR Gene Editor for Human Cells From Scratch"},"content":{"rendered":"<p>CRISPR has revolutionized science. AI is now taking the gene editor to the next level.<\/p>\n<p>Thanks to its ability to accurately edit the genome, CRISPR tools are now widely used in biotechnology and across medicine to tackle inherited diseases. In late 2023, a therapy using the\u00a0<a href=\"https:\/\/www.scientificamerican.com\/article\/nobel-prize-in-chemistry-goes-to-discovery-of-genetic-scissors-called-crispr-cas911\/\">Nobel Prize-winning<\/a>\u00a0tool gained approval from the FDA to treat sickle cell disease. CRISPR has also enabled\u00a0<a href=\"https:\/\/singularityhub.com\/2024\/04\/19\/cell-therapies-can-now-beat-back-once-untreatable-blood-cancers-scientists-are-making-them-even-deadlier\/\">CAR T cell therapy to battle cancers<\/a>\u00a0and been used to\u00a0<a href=\"https:\/\/singularityhub.com\/2023\/11\/21\/breakthrough-crispr-treatment-slashes-cholesterol-in-first-human-clinical-trial\/\">lower dangerously high cholesterol levels<\/a>\u00a0in clinical trials.<\/p>\n<p>Outside medicine, CRISPR tools are\u00a0<a href=\"https:\/\/singularityhub.com\/2022\/10\/26\/from-pitless-cherries-to-softer-kale-this-startup-is-using-crispr-to-make-better-produce\/\">changing the agricultural landscape<\/a>, with projects ongoing to engineer\u00a0<a href=\"https:\/\/singularityhub.com\/2019\/10\/22\/crispr-just-created-a-hornless-bull-and-its-a-step-forward-for-gene-edited-food\/\">hornless bulls<\/a>,\u00a0<a href=\"https:\/\/www.nature.com\/articles\/s41477-022-01154-6\">nutrient-rich tomatoes<\/a>, and\u00a0<a href=\"https:\/\/www.technologyreview.com\/2023\/01\/20\/1067125\/crispr-farmed-animals-bigger-stronger-healthier\/\">livestock and fish<\/a>\u00a0with more muscle mass.<\/p>\n<p>Despite its real-world impact, CRISPR isn\u2019t perfect. The tool snips both strands of DNA, which can cause dangerous mutations. It also can inadvertently nip unintended areas of the genome and trigger unpredictable side effects.<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/singularityhub.com\/2024\/04\/25\/this-ai-just-designed-a-more-precise-crispr-gene-editor-for-human-cells-from-scratch\/\">https:\/\/singularityhub.com\/2024\/04\/25\/this-ai-just-designed-a-more-precise-crispr-gene-editor-for-human-cells-from-scratch\/<\/a>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>CRISPR has revolutionized science. AI is now taking the gene editor to the next level. Thanks to its ability to accurately edit the genome, CRISPR tools are now widely used in biotechnology and across medicine to tackle inherited diseases. In late 2023, a therapy using the\u00a0Nobel Prize-winning\u00a0tool gained approval from the FDA to treat sickle [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[16],"tags":[],"_links":{"self":[{"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/posts\/1824"}],"collection":[{"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/comments?post=1824"}],"version-history":[{"count":1,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/posts\/1824\/revisions"}],"predecessor-version":[{"id":1825,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/posts\/1824\/revisions\/1825"}],"wp:attachment":[{"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/media?parent=1824"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/categories?post=1824"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jonathandespres.com\/cryonicsrevival\/wp-json\/wp\/v2\/tags?post=1824"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}